Fakultas Kedokteran Gigi

Fibromatous Gingival Epulis : A Case Report

2023-04-11T06:56:26Z

Fibromatous Gingival Epulis : A Case Report Rizka, Yoifah; Nilawati, Nina; Widyastuti; Kuniawan, Hansen; Prameswari, Dianty; Yoyada, Novendy; Victoria, Onge Abstract Background: Epulis is a generic term that is used to clinically designate all discrete tumors and tumor-like masses of the gingiva. Fibromatous epulis is a hyperplastic reaction of fibrous connective tissue due to chronic stimulation or irritation, such as calculus or sharp parts of the retained root. The mass was pedunculated, pale pink in color, solid consistency, the boundary was firm, and was not easy to bleed with no pain. Objective : Discuss the management of fibromatous epulis by excision Case :A 25-year-old male patient who suffered from unusual unilateral, gingival enlargement in lingual anterior mandible. The masses appeared since a year ago, initially small and gradually grew to the size 3 cm, solid consistency, well-defined, not easy to bleed, and not painful. The patient was diagnosed with fibromatous epulis and chronic periodontitis based on the clinical, histological, and radiographic findings. The mass has been treated by excision. Case Management :The gingival enlargement was treated by conventional gingivectomy under local anaesthesia.The postoperative result was uneventful. Conclusion : The excision of fibromatous epulis was carried out to remove the mass and eliminating the predisposed factor.

THE USE OF ELECTRO SURGERY FOR EXCISION THE GINGIVAL TUMOR: Case Report

2023-04-07T16:52:21Z

THE USE OF ELECTRO SURGERY FOR EXCISION THE GINGIVAL TUMOR: Case Report Rizka, Yoifah; Nilawati, Nina Introduction: The gingiva tumor often called epulis, caused by uncontrolled growth due to excessive or continuous stimulation of the gingiva. Epulis treatment is to remove the tumor by means of either excision with a scalpel, laser or electro surgery. Objective:This case report aims to provide information the use of electro surgery for excision the gingival tumor. Case 1: A25-years-old woman, present with tumor in the lower jaw gum. Tumor arise since 1 year ago, not pain but interfere. The surface of tumor shiny, reddish, clear boundaries, dense chewy and fixed.Case 2:A 46-yeas-old female patient with tumor diameter of 3mm on the gum region 16. Tumor arise since 3 year ago with the longer growing.The surface of the tumor, shiny, pale, no pain and no bleed easily. In both patients do not obtain systemic abnormalities and there is no alveolar bone loss in radiographic examination. Case Management:Excision of the tumor with electro surgery, after examination with Fine Needle Aspiration (FNA) biopsy showed no sign of malignancy. Conclusion: The use of electro surgery for excision the gingival tumor does not cause bleeding and no need periodontal pack, but the healing longer than excision with a scalpel. Keywords:gingival tumor, excision, electro surgery, no bleeding.

The Effects of High Pressure Oxygen Therapy in Osteocytes Alveolar Bone of Diabetes Mellitus Wistar Rat Induced by Porphyromonas Gingivalis

2023-04-07T16:27:20Z

The Effects of High Pressure Oxygen Therapy in Osteocytes Alveolar Bone of Diabetes Mellitus Wistar Rat Induced by Porphyromonas Gingivalis Rizka, Yoifah; Wijaya, Lani Febrianti; Mulawarmanti, Dian : Periodontitis is one of oral complication that commonly found in patients with Diabetes Mellitus. One of the bacteria that causing this disease is Porphyromonas gingivalis (P.g). Handling periodontitis with Diabetes Mellitus does not include local factors only, but also systemic factors such as handling of blood sugar because therapy of periodontitis in patients with systemic disease also has the potential to improve overall general conditions. Mechanical periodontitis teraphy can be carried out by scaling and root planing (SRP) but the healing it does not indicate the new connective tissue attachment. High pressure oxygen teraphy (HBOT), teraphy with breathing using 100% oxygen in high pressure chamber (more than 1 ATA), can accelerate alveolar bone healing as part of health tissue regeneration Purpose: To prove the effects of high pressure oxygen teraphy in the increasing of alveolar bone osteocytes of rat with DM induced by P.g. Materials and Methods: This research adopts post test only control group design. Fifteen male wistar rats are divided into three groups. K- ( negative control group), K1: induced by P.g and Streptozotocin, and K2: induced by P.g, Streptozotocin, high pressure oxygen teraphy 2,4 ATA 100% O2 3x30 minutes with five minute interval of air inhalation for five consecutive days. Results: Kruskal-Wallis test (p<0,05) and Mann-Whitney U (p>0,05) shows decreasing of osteocytes of alveolar bone significantly in K1 (3,55±0,93) that compared with K0 (5,33±2,32), increasing significantly in K2 (5,40±1,51) that compared with K1 (3,55±0,93), and no main changes between K2 (5,40±1,51) and K0 (5,33±2,32). Conclusion: HBOT 2,4 ATA 100% O2 3x30’ with 5’ interval of air inhalation for five consecutive days can increase of alveolar bone osteocytes of rat with DM induced by P.g.

Prosthetic Rehabilitation of a Partially Edentulous Patient with Chronic Periodontitis

2022-06-22T01:12:31Z

Prosthetic Rehabilitation of a Partially Edentulous Patient with Chronic Periodontitis Nanik.K, Chaterina Diyah Background: One of the most common inflammation disease in the oral cavity for the past few years is the chronic form of periodontitis. Patients with chronic periodontitis, who her jobs requires to interact with people are a real challenge for the dentist and the prosthetis. The problem with the traditional method is the fact that for rehabilitation of patients who have lost their tooth/teeth , has to be waited for approximately 8 to 12 weeks before having their dentures. There are many advantages of immediate as opposed to conventional complete denture. Hence, dentists have no opportunity to observe the anterior teeth at the try in appointment; therefore, the esthetic result cannot be evaluated until the dentures are inserted. Purpose: The prosthetic rehabilitation of a partially edentulous patient with chronic periodontitis using immediate maxillary full denture and immediate mandibular partial overdenture. Case and Case management: We presented a patient suffered from chronic periodontitis with major complain of her teeth mobility, mostly anterior teeth. She had undergone periodontal treatment, but the result were bad. In maxilla, at the end of peridontal treatment, all of her teeth need to be extracted and replaced by dentures. In mandible, there were some teeth that can be used as abutment for an overdenture, so we decided to place immediate partial overdenture in mandible with consideration both of her functional and esthetic aspects. Conclusion: One of the advantages of immediate dentures is patients don’t have to be in edentulous state for any length of time. After treatment, patient was evaluated, fortunately she had no complaints and was happy with her new smile.

How to Manage The Mucocele on The Lower Lips

2021-10-07T03:15:07Z

How to Manage The Mucocele on The Lower Lips Nilawati, Nina

Tips Pemasangan Implan Gigi Bagi Pemula

2021-10-06T07:27:33Z

Tips Pemasangan Implan Gigi Bagi Pemula Nilawati, Nina

Nicotine Effect on The Number of Osteclast and Osteoblast After Dental Implant Placement

2021-10-06T06:58:14Z

Nicotine Effect on The Number of Osteclast and Osteoblast After Dental Implant Placement Nilawati, Nina

Management of Primary Herpetic Gingivostomatitis in Child

2021-04-21T07:19:19Z

Management of Primary Herpetic Gingivostomatitis in Child Priambodo, Nur Tsurayya; Radithia, Desiana; Hadi, Priyo

PORCELAIN ONLAY RESTORATION ON THE FIRST LOWER MOLAR AFTER ROOT CANAL TREATMENT

2021-02-10T21:58:02Z

PORCELAIN ONLAY RESTORATION ON THE FIRST LOWER MOLAR AFTER ROOT CANAL TREATMENT Cevanti, Twi Agnita; Aprilia, Aprilia Background : This paper is a case repor of porcelain onlay restoration which was made on the first lower molar after root canal treatment. Onlay is an alternative for endodontically treated teeth it provides cuspal protection, this type of restoration sometimes called a partial crown. Case is a female patient, age 19 years old with pulp necrosisin the maxillary lower teeth. This case report describes a minimal invasive, aesthetc solution to provide cuspal coverage after root canal treatment Case Management : The restoration were examinated for marginal integrity, anatomis form, surface and color for a period of 12 months. This restoration was in function at the end of evaluation periode. There was adverse event the all porcelain restoration exhibited the least plaque growth, have excellent biocompatibility, inertness, improved physical bonding and natural appearence.

PERIODONTAL INFECTION AND DIABETES: MAKING THE CONNECTIONS IN TWO WAYS

2021-02-09T15:18:34Z

PERIODONTAL INFECTION AND DIABETES: MAKING THE CONNECTIONS IN TWO WAYS Rizka, Yoifah Abstract. Recent attention has been focused on our understanding of the negative influences of oral chronic inflammation on systemic health. There is growing evidence that periodontal diseases may affect general health. Periodontal diseases have powerful and multiple influences on the occurence and severity of systemic conditions and disesases, such a diabetes mellitus, cardiovascular diseases, respiratory diseases, and pregnancy complications. The relationship of periodontitis and diabetes has been supported by sufficent evidences in the past twenty years and has long been discussed with conflicting conclusions. Both'of these diseases have a relatively high incidence globally in the general population with a number of common pathways in their pathogenesis. Their relationship appears bi-directional insofar that the presence of one condition tends to promote the other, and that the appropriate management of either may assist treatment of the other. However, the converse possibility that periodontal disease either predisposes or exacerbates the diabetic condition has received little attention, and it is only less known about the impact of periodontal diseases on the diabetes-related inflammatory state. Although type 2 diabetes is a multiple risk-factor syndrome, lowered insulin sensitivity, called insulin resistance, is essential in developing the disease. Proinflammatory cytokine produced from chronic inflammation subjects as periodontitis, is known to playa predominant rolein inducinginsulinresistance. ' This review attempts to explain the immunobiological connection between periodontal disease and diabetes mellitus type 2, exploring the mechanisms through which periodontal infection can contribute to the low-grade general inflammation associated with diabetes (thus worsening insulin resistance) and discussing the impact of periodontal treatment on glycemic control in people livingwith both diabetes and periodontal disease.

Host Modulatory Therapy in Aggressive Periodontitis

2021-02-09T15:06:37Z

Host Modulatory Therapy in Aggressive Periodontitis Widyastuti, Widyastuti Abstract Host modulatory therapy (HMTs) ia a treatment concept that goal to reduce tissue destruction and stabilize or even regenerate the periodontium. The aggressive periodontitis result in rapid destruction of the periodontium and can lead to early bone destruction, until tooth loss. HMTs modifying or downregulating dectructive aspects and upregulating protective aspectc of the host response, in combination with conventional treatments to reduce the bacterial burden, the balance between health and disease progression is tipped in the direction of a healing response. Many aspects of the host response can be affected, including modification of proteolytic enzymes such as matrix metalloproteinases, stimulation of cellular activity, and alteration of the extracellular matrix, all these aspects can be considered as host modulation. HMTs are systemically or locally delivered pharmacheuticals that are prescribed as part of periodontal therapy and are used as adjuncts to conventional periodontal treatments. A variety of different drug classes have been evaluated as host modulation agents, including the nonsteroidal antiinflammatory drugs (NSAIDs), biphosphonates, chemically modified tetracyclines (CMTs) or subantimicrobial-dose doxycycline (SDD). The concept of periodontal medicine is not only the bacterial challenge by scaling and rootplaning (SRP) but also the host side of the host-bacterial interactions. Subantimicrobial-dose doxycycline (SDD) is the only HMTs currently approved and indicated as an adjunct to SRP for treating aggressive periodontitis.

Effect of Avicennia marina sp leaf extract to rat gingival catalase level induced by mix periodontopathogen bacteria

2021-02-09T14:48:03Z

Effect of Avicennia marina sp leaf extract to rat gingival catalase level induced by mix periodontopathogen bacteria Widyastuti, Widyastuti ABSTRACT Background : Periodontal disease is the second largest oral disease in Indonesia population caused by infection of periodontopathogen bacteria. Most of the bacteria of periodontitis are Gram negative anaerobic bacteria. Avicennia marina sp is a natural product that has some medical potential regarding to its nutritional contents including antioxidant activity. Objectives : The aim of this study is to investigate the effect of Avicennia marina sp extract on catalase activities in gingival Wistar rats induced mix periodontopathogen bacteria. Methods: The experiment was held by post test only control group design. Fivety male Wistar rats divided into five group. Group-1 group was negative control group, group-2 group was a positive control group, and the other groups were induced by mixed periodontopathogen bacteria and treated with Avicennia marinaspleaf extract on various concentration. After treatment, the rats were sacrificed. Gingival catalase level (mg/ml) of each group was measured. All of datas were analyzed by one way ANOVA and LSD multiple comparison test at 5% significance level. Result: This study showed that gingival catalase level was significantly lower in group-2 than group-1. Gingival catalase level in treatment group was significantly higher than control positive group. Conclusion: Avicennia marina sp leaf extract can increase rat gingival catalase level.

CITOTOXICITY OF MANGROVE RHIZOPORA MUCRONATA BARK EXTRACTS AS INTRACANAL MEDICAMENT

2021-01-09T12:35:13Z

CITOTOXICITY OF MANGROVE RHIZOPORA MUCRONATA BARK EXTRACTS AS INTRACANAL MEDICAMENT Cevanti, Twi Agnita; Aprilia, Aprilia Introduction: A root canal disinfectant should be antimicrobial agent effective in eliminating and prohibiting microorganism growth with no toxicity towards periradicular tissues. Rhizophora mucronata bark extracts have been found in previous studies to exhibit antibacterial activity. Objectives: This study aims to determine the cytotoxicity of Rhizophora mucronata bark extracts as an intracanal medicament. Method: Gingival mesenchymal stem cells (GMSCs) were exposed to the Rhizophora mucronata bark extracts at different concentrations of 0.5% (Group 1), 1% (Group 2), 2.5% (Group 3), 5% (Group 4), 10% (Group 5), and 20% (Group 6) to assess its cytotoxic effect. In addition, there were two control groups; one containing only the culture medium while another only with the cells. Cell viability was assessed by 3-(4, 5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. This was done by adding MTT solution into each well after 3 minutes and then incubating them for 4 hours. Dimethylsulfoxide (DMSO) was then added to each well and shaken to mix. The absorbance was then measured on an ELISA plate reader with a reference wavelength of 630 nm. The extract at that said concentration is identified to be non-toxic if the cell viability is ≥ 50 %. Results: There was significant difference in cell viability of the GMSCs at various concentrations of the extract. The highest cell viability was found in group of cells which was treated with 1% concentration of Rhizopora Mucronata extract, while the with 10% concentration Rhizopora Mucronata significantly reduced the cell viability to the lowest among all groups. Conclusion: Rhizophora mucronata bark extracts at concentrations of 0.5%, 1%, 2.5%, and 5% can be used safely as endodontic intracanal medicament.

Cytoxicity Test of Diadema Setosum Shell Extract Againts Fibroblast Culture Cell

2021-01-09T12:08:42Z

Cytoxicity Test of Diadema Setosum Shell Extract Againts Fibroblast Culture Cell Irawati, Novi Virina; Aprilia, Aprilia; Ashrin, Meinar Nur Background: Calcium is one of the basic ingredients of calcium hydroxide which is used in the field of dentistry as pulp capping material. Utilization of shells to be used as biomaterials Diadema setosum new to the field of dentistry, because one of the ingredients in Diadema setosum shells is calcium. Purpose: To find out the cytotoxicity of Diadema setosum shell extract against fibroblast cell cultures. Material and Methods: This research was carried out by using post test only control group design. Fibroblasts cultured in 96 wells were divided into a control group of cells (n=6), media control (n=6) and treatment (n=6). Treatment groups were given various doses extract with concentration of shells Diadema setosum 125 μg, 250 μg, 500 μg, 1000 μg, 2000 μg. Optical density was read with an ELISA reader and calculated the percentage of viability. The cell viability data were analyzed by One-way ANOVA statistical test and LSD. Result: Data indicate decreased cell viability in all treatment groups, level of concentration of the extract by Diadema setosum shell, that is 125 μg(83.7%), 250 μg(81.9%), 500 μg(66.25%), 1000 μg(57.08%), 2000 μg(42.95%). There is a significant difference (p=0.000) in all treatment groups after analyzed by using One-way ANOVA. Conclusion: Diadema setosum shell extract do not have toxic effects on cultured fibroblast cells at concentrations 125 μg, 250 μg, 500 μg, 1000 μg and has toxic effects on cultured fibroblast cells at the highest concentration, that is 2000 μg.

IN VITRO CYTOTOXICITY EVALUATION OF Nannochloropsis occulata sp EXTRACTTO HUMAN GINGIVAL FIBROBLAST STEM CELLS

2020-12-03T06:04:14Z

IN VITRO CYTOTOXICITY EVALUATION OF Nannochloropsis occulata sp EXTRACTTO HUMAN GINGIVAL FIBROBLAST STEM CELLS Revianti, Syamsulina; Parisihni, Kristanti

Effect of avicennia marina sp leaf extract to rat gingival catalase level induced By mix periodontopathogen bacteria

2020-12-03T05:42:22Z

Effect of avicennia marina sp leaf extract to rat gingival catalase level induced By mix periodontopathogen bacteria Widyastuti; Revianti, Syamsulina

BIOACTIVITY OF STICHOPUS HERMANII TO BMP-2 EXPRESSION IN RELAPSE ORTHODONTIC (Fulltext of Oral Presentation)

2020-10-26T06:26:55Z

BIOACTIVITY OF STICHOPUS HERMANII TO BMP-2 EXPRESSION IN RELAPSE ORTHODONTIC (Fulltext of Oral Presentation) Prameswari, Noengki; Revianti, Syamsulina; Brahmanta, Arya

ANTI INFLAMATORYEFFECT OF STICHOPUS HERMANII EXTRACT AS ORAL CANDIDIASIS TREATMENT

2020-10-26T05:18:23Z

ANTI INFLAMATORYEFFECT OF STICHOPUS HERMANII EXTRACT AS ORAL CANDIDIASIS TREATMENT Revianti, Syamsulina; Parisihni, Kristanti; Pringgenies, Delianis

Integrin Α2β1 And Bmp-2 Regulated In Bone Remodelling To Accelerate Orthodontic Tooth Movement By Giving Stichopus Hermanii

2020-10-07T16:18:56Z

Integrin Α2β1 And Bmp-2 Regulated In Bone Remodelling To Accelerate Orthodontic Tooth Movement By Giving Stichopus Hermanii Prameswari, Noengki; Brahmanta, Arya

Daya Hambat Ekstrak Kulit Batang Bakau Besar (Rhizophora mucronata) Terhadap Pertumbuhan Bakteri Enterococcus faecalis

2020-04-20T13:41:30Z

Daya Hambat Ekstrak Kulit Batang Bakau Besar (Rhizophora mucronata) Terhadap Pertumbuhan Bakteri Enterococcus faecalis baraja, muhammad; cevanti, twi agnita; parisihni, twi agnita Latar Belakang : Enterococcus faecalis merupakan bakteri anaerob fakultatif gram positif yang paling banyak ditemukan pada perawatan endodontik yang gagal. ChKM adalah obat sterilisasi saluran akar yang sering digunakan. Ekstrak kulit batang Rhizophora mucronata memiliki sifat antibakteri spektrum luas yang dapat menghambat pertumbuhan bakteri gram positif maupun gram negatif., sehingga dapat berpotensi untuk dikembangkan sebagai obat sterilisasi saluran akar. Tujuan : Mengetahui kemampuan ekstrak kulit batang Rhizophora mucronata dalam menghambat pertumbuhan bakteri Enterococcus faecalis. Metode : Penelitian ini merupakan penelitian eksperimental dengan desain penelitian post test only control group, terdiri dari 8 kelompok yaitu: satu kelompok kontrol positif (ChKM), satu kelompok kontrol negatif (DMSO 1%), dan enam kelompok perlakuan dengan konsentrasi ekstrak kulit batang Rhizophora mucronata yang berbeda yaitu 2,5 mg/ml, 5 mg/ml, 10 mg/ml, 20 mg/ml, 40 mg/ml, dan 80 mg/ml dimana setiap kelompok terdiri dari 16 sampel. Daya hambat diperiksa dengan mengukur diameter zona jernih di sekeliling kertas saring. Analisis data menggunakan uji Kruskall-Wallis dan diikuti dengan uji Mann-Whitney. Hasil : Hasil penelitian ini menunjukan adanya daya hambat dari ekstrak kulit batang Rhizophora mucronata. Dalam penelitian ini, semakin tinggi konsentrasi yang digunakan, maka semakin besar daya hambatnya. Rata-rata zona hambatnya yaitu: 2,5 mg/ml (6,56mm), 5 mg/ml (6,83mm), 10 mg/ml (7,27mm), 20 mg/ml (7,77mm), 40 mg/ml (8,29mm), 80 mg/ml (9,23mm), ChKM (20,55mm), DMSO 1% (6,01mm). Kesimpulan : Ekstrak kulit batang Rhizophora mucronata dapat menghambat pertumbuhan bakteri Enterococcus faecalis.

sitotoksisitas ekstrak daun mangrove daruju (Acantus ilicifolius) sebagai bahan irigasi saluran akar

2020-04-20T13:02:34Z

sitotoksisitas ekstrak daun mangrove daruju (Acantus ilicifolius) sebagai bahan irigasi saluran akar ratna putri; cevanti, twi agnita; sumekar, Henu Latar belakang: Pembersihan dan pembentukan saluran akar merupakan tahapan penting pada perawatan saluran akar. Bahan irigasi diperlukan pada tahapan tersebut untuk membersihkan jaringan nekrotik, partikel dentin dan mikroorganisme. Syarat bahan irigasi saluran akar antara lain mampu melarutkan debris atau sisa jaringan, memiliki tegangan permukaan rendah, dan tidak bersifat toksik. Mangrove daruju (Acanthus ilicifolius) memiliki potensi untuk dikembangkan sebagai alternatif bahan irigasi saluran akar karena hasil fitokimia ekstrak daunnya menunjukan kandungan saponin, alkaloid, terpenoid dan tannin yang berpotensi sebagai antimikroba. Tujuan: Penelitian ini bertujuan untuk mengetahui sitotoksisitas ekstrak daun Acanthus ilicifolius terhadap kultur sel fibroblas BHK-21 Metode: Sampel yang digunakan adalah sel fibroblas BHK-21 dengan metode kultur, diberi perlakuan ekstrak kloroform daun Acanthus ilicifolius dengan berbagai konsentrasi. Sampel dibagi menjadi 7 kelompok, 1:kontrol sel, 2: kontrol media, 3: 40mg/ml, 4: 50mg/ml, 5: 60mg/ml, 6: 70mg/ml, 7: 80mg/ml. Kemudian larutan MTT ditambahkan, 3 menit kemudian dilakukan inkubasi selama 4 jam. Larutan DMSO ditambahkan kemudian dikocok, sampel diperiksa menggunakan ELISA reader panjang gelombang 620. Sitotoksisitas dinyatakan dengan viabilitas sel, apapila >50%, maka tidak toksik. Data dianalisa menggunakan uji non parametrik (Kruskal-Wallis) dilanjutkan uji Mann-Whitney. Hasil: Uji Kruskal-Wallis membuktikan bahwa terdapat perbedaan viabilitas sel yang bermakna antar kelompok perlakuan. Beda rerata antar kelompok diuji dengan Mann-Whitney memperlihatkan perbedaan bermakna pada kelompok 1 dengan 5 dan kelompok 2 dengan 5. Kesimpulan: Ekstrak klorofom daun Acanthus ilicifolius tidak bersifat toksik terhadap kultur sel fibroblas BHK-21.

Cytotoxicity of mangrove rhizhopora mucronate bark extracts as intracanal medicament

2020-04-20T12:36:24Z

Cytotoxicity of mangrove rhizhopora mucronate bark extracts as intracanal medicament cevanti, twi agnita Objectives : This study aims to determine the cytotoxicity of Rhizophora mucronata bark extracts as an intracanal medicament. Materials and Methods: Gingival mesenchymal stem cells (GMSCs) were exposed to the Rhizophora mucronata bark extracts at different concentrations of 0.5% (Group 1), 1% (Group 2), 2.5% (Group 3), 5% (Group 4), 10% (Group 5), and 20% (Group 6) to assess its cytotoxic effect. In addition, there were two control groups; one containing only the culture medium while another only with the cells. Cell viability was assessed by 3-(4, 5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. This was done by adding MTT solution into each well after 3 minutes and then incubating them for 4 hours. Dimethylsulfoxide (DMSO) was then added to each well and shaken to mix. The absorbance was then measured on an ELISA plate reader with a reference wavelength of 630 nm. The extract at that said concentration is identified to be non-toxic if the cell viability is ≥ 50 %. Result: There was significant difference in cell viability of the GMSCs at various concentrations of the extract. The highest cell viability was found in group of cells which was treated with 1% concentration of Rhizopora Mucronata extract, while the with 10% concentration Rhizopora Mucronata significantly reduced the cell viability to the lowest among all groups. Conclusion: Rhizophora mucronata bark extracts at concentrations of 0.5%, 1%, 2.5%, and 5% can be used safely as endodontic intracanal medicament.

The effect of oxygenation on apoptosis of the fibroblast cell in periodontal issue rats

2020-02-06T01:57:52Z

The effect of oxygenation on apoptosis of the fibroblast cell in periodontal issue rats Mulawarmanti, Dian; Revianti, Syamsulina; Laihad, Fanny

The effect of hyperbaric oxygen therapy the regulator nitric oxida production on wound healing

2020-02-06T01:52:55Z

The effect of hyperbaric oxygen therapy the regulator nitric oxida production on wound healing Mulawarmanti, Dian

The Effect of Sardinella Longiceps Oil To The Haemoglobine Rate At Hypercholesterolemic Rattus Novergicus Strain Wistar Male

2019-12-20T03:48:56Z

The Effect of Sardinella Longiceps Oil To The Haemoglobine Rate At Hypercholesterolemic Rattus Novergicus Strain Wistar Male Prameswari, Noengki

The Effect of Sticopus Hermanni to Osteoclast Tension Site Activity In Relapse Orthodontic

2020-10-07T15:41:53Z

The Effect of Sticopus Hermanni to Osteoclast Tension Site Activity In Relapse Orthodontic Prameswari, Noengki; Revianti, Syamsulina; Brahmanta, Arya

Bioactivity Of Anadara Granosa Shell Waste and Soy Milk To Alveolar Bone Height

2019-12-20T03:11:33Z

Bioactivity Of Anadara Granosa Shell Waste and Soy Milk To Alveolar Bone Height Prameswari, Noengki; Puguh, Bayu Prabowo; Syamsulina, Revianti

Application Nanopowder Stichopus Hermanii To Prevent Relaps Orthodontis by Periodontal Ligament Remodelling

2019-12-20T02:59:14Z

Application Nanopowder Stichopus Hermanii To Prevent Relaps Orthodontis by Periodontal Ligament Remodelling Prameswari, Noengki; BP, Puguh; Sudibyo

Kebutuhan Perawatan Ortodontik Anak Penderita Tunarungu Berdasarkan Pengukuran DHC dan AC Indeks Iotn

2020-10-07T15:54:36Z

Kebutuhan Perawatan Ortodontik Anak Penderita Tunarungu Berdasarkan Pengukuran DHC dan AC Indeks Iotn Prameswari, Noengki; Ertiana, Ika

IL-17 Expression in Oral-Candidiasis-Immunosuppressed-Models treated with Acanthus Ilicifolius Extracts

2019-04-15T04:44:29Z

IL-17 Expression in Oral-Candidiasis-Immunosuppressed-Models treated with Acanthus Ilicifolius Extracts Andriani, Dwi; Revianti, Syamsulina Objective(s). Immunosuppressed conditions are susceptible for fungal invasion. Candida albicans (C.albicans) are the most prevalent species that caused oral candidiasis. IL-17 pathway play role in antifungal immunity. Acanthus ilicifolius (A.ilicifolius)’s leaves chloroform extracts has antifungal agent against C.albicans growth. Nystatin is regularly used for oral candidiasis. The aim of this study was to compare treatment effect of A.ilicifolius’s leaves extracts with nystatin on IL-17 expression in oral candidiasis immunosupressed model. Method(s). This study was true experimental with post test only control group design. Sixteen male Ratus Novergicus Wistar strain, aged 12 weeks, average 250g weight and healthy were immunosuppressed with dexamethasone (0,5mg/day) and tetracycline (1mg/day) orally for 7 day, after that induced by C.albicans (ATCC-10231) 6x108 on the tongue of rats for 2 weeks (3 times/week). Rats divided into four groups (n=4/group): no-treatment(G1), nystatin-treatment(G2), A.Ilicifollius(8%)-Treatment-2(G3), and A.Ilicifollius(16%)- Treatment(G4). The rats was treated for 14 days. After treated the tongue were biopsied and IL-17 expression were examined by immunohistochemistry. The result observed using microscope(400x magnification) and statistically analyzed (One-way ANOVA, LSD-test, p˂0,05). Result(s). IL-17 expression of G2(11,5±1,29), G3(13,7±2,06) and G4(13,5±2,08) are higher than G1(3,5±1,29).There was no significant differences between G2 to G3 and G4(p˃0,05). Conclusion(s). A.ilicifolius extract can increase expression of IL-17 in oral-Candidiasis-immunosupressed-model. A.ilicifolius extract has the same effect compare with nystatin.